Join Dr Carmine Gentile as he discusses his exciting work using stem cells from patients plus 3D bioprinters to fabricate heart tissues.
3D bioprinting technology has emerged in the past 15 years as a tool for the generation of human tissues and organs for transplantation and drug testing. Dr Gentile’s team has developed a technology that uses stem cells isolated from patients together with 3D bioprinters to fabricate heart tissues. In this process, cardiac bioinks are formed by mixing cells with hydrogels that mimic the microenvironment typical of the human heart. Bioinks are then extruded through the nozzle of a 3D bioprinter that generates viable and functional heart tissues.
Currently, 3D bioprinted tissues are used for drug testing and toxicity studies and for disease modelling of heart damage (such as, heart attacks in a Petri dish). Dr Gentile’s team is also testing how to transplant 3D bioprinted heart tissues in a safe way for the regeneration of damaged heart tissues in patients.
We are pleased to present this online Science in Focus talk in partnership with the Sydney Science Trail as part of National Science Week.
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